Normative data on spontaneous stride velocity, stride length, and walking activity in a non-controlled environment.

ABSTRACT:

Background

Normative data are necessary for validation of new outcome measures. Recently, the 95th centile of stride speed was qualified by the European Medicines Agency as a valid secondary outcome for clinical trials in subjects with Duchenne muscular dystrophy. This study aims to obtain normative data on spontaneous stride velocity and length in a non-controlled environment and their evolution after 12 months.

Method

Ninety-one healthy volunteers (50 females, 41 males), with a mean age of 16 years and 2 months, were recruited and assessed at baseline and 12 months later. The 4-stair climb, 6-min walk test, 10-m walk test and rise from floor assessments were performed. Stride length, stride velocity, and the distance walked per hour were studied in an everyday setting for

SUBMITTER: Poleur M 

PROVIDER: S-EPMC8287788 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature