Use of Procalcitonin in a Febrile Infant Clinical Pathway and Impact on Infants Aged 29 to 60 Days.

ABSTRACT:

Objectives

Recent evidence suggests that measuring the procalcitonin level may improve identification of low-risk febrile infants who may not need intervention. We describe outcomes after the implementation of a febrile infant clinical pathway recommending measurement of the procalcitonin level for risk stratification.

Methods

In this single-center retrospective pre-post intervention study of febrile infants aged 29 to 60 days, we used interrupted time series analyses to evaluate outcomes of lumbar puncture (LP), antibiotic administration, hospital admission, and emergency department (ED) length of stay (LOS). A multivariable logistic regression was used to evaluate the odds of LP.

Results

Data were analyzed between January 2017 and December 2019 and included 740 part

SUBMITTER: Widmer K 

PROVIDER: S-EPMC8287898 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature