Architecture and evolution of subtelomeres in the unicellular green alga Chlamydomonas reinhardtii.

ABSTRACT: In most eukaryotes, subtelomeres are dynamic genomic regions populated by multi-copy sequences of different origins, which can promote segmental duplications and chromosomal rearrangements. However, their repetitive nature has complicated the efforts to sequence them, analyse their structure and infer how they evolved. Here, we use recent genome assemblies of Chlamydomonas reinhardtii based on long-read sequencing to comprehensively describe the subtelomere architecture of the 17 chromosomes of this model unicellular green alga. We identify three main repeated elements present at subtelomeres, which we call Sultan, Subtile and Suber, alongside three chromosome extremities with ribosomal DNA as the only identified component of their subtelomeres. The most common architecture, present in 27

SUBMITTER: Chaux-Jukic F 

PROVIDER: S-EPMC8287924 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature