Initial Patterns of Prescription Opioid Supply and Risk of Mortality Among Insured Adults in the United States.

ABSTRACT:

Objective

To examine the association between initial patterns of prescription opioid supply (POS) and risk of all-cause mortality among an insured opioid-naïve patient population in the United States (US).

Methods

This retrospective observational cohort study used de-identified, administrative health care claims data from a large national insurer (Optum Clinformatics Data Mart) from 2010 to 2015. Participants included insured, cancer-free adults prescribed opioid analgesics. Prescription opioids received during the first 6 months of therapy were used to categorize initial patterns of POS as daily or nondaily. Cox regression was used to estimate the association of initial patterns of POS with all-cause mortality within one year of follow-up, adjusting for baseline covariates

SUBMITTER: Aroke HA 

PROVIDER: S-EPMC8288109 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature