Cross-sectional study of preprints and final journal publications from COVID-19 studies: discrepancies in results reporting and spin in interpretation.

ABSTRACT:

Objective

To compare results reporting and the presence of spin in COVID-19 study preprints with their finalised journal publications.

Design

Cross-sectional study.

Setting

International medical literature.

Participants

Preprints and final journal publications of 67 interventional and observational studies of COVID-19 treatment or prevention from the Cochrane COVID-19 Study Register published between 1 March 2020 and 30 October 2020.

Main outcome measures

Study characteristics and discrepancies in (1) results reporting (number of outcomes, outcome descriptor, measure, metric, assessment time point, data reported, reported statistical significance of result, type of statistical analysis, subgroup analyses (if any), whether outcome was identified as primar

SUBMITTER: Bero L 

PROVIDER: S-EPMC8288242 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature