Interpregnancy intervals and adverse birth outcomes in high-income countries: An international cohort study.

ABSTRACT:

Background

Most evidence for interpregnancy interval (IPI) and adverse birth outcomes come from studies that are prone to incomplete control for confounders that vary between women. Comparing pregnancies to the same women can address this issue.

Methods

We conducted an international longitudinal cohort study of 5,521,211 births to 3,849,193 women from Australia (1980-2016), Finland (1987-2017), Norway (1980-2016) and the United States (California) (1991-2012). IPI was calculated based on the time difference between two dates-the date of birth of the first pregnancy and the date of conception of the next (index) pregnancy. We estimated associations between IPI and preterm birth (PTB), spontaneous PTB, and small-for-gestational age births (SGA) using logistic regression (betwe

SUBMITTER: Tessema GA 

PROVIDER: S-EPMC8289039 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature