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Healthcare workers acquired COVID-19 disease from patients? An investigation by phylogenomics.


ABSTRACT: The increasing number of coronavirus disease 2019 (COVID-19) cases in the community has posed a significant epidemic pressure on healthcare settings. When healthcare workers (HCWs) acquire COVID-19, contact tracing and epidemiological investigation might not be adequate for determining the source of transmission. Here, we report a phylogenetic investigation involving two infected HCWs and nine patients to determine whether patient-to-HCW transmission had occurred in a hospital without a previous COVID-19 outbreak. This is the first study to apply phylogenomics to investigate suspected nosocomial transmission in a region with low prevalence of COVID-19. Our results do not support the occurrence of direct patient-to-HCW transmission.

SUBMITTER: Wong RCW 

PROVIDER: S-EPMC8289439 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature

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Healthcare workers acquired COVID-19 disease from patients? An investigation by phylogenomics.

Wong R C W RCW   Lee M K P MKP   Siu G K H GKH   Lee L K LK   Leung J S L JSL   Leung E C M ECM   Ho Y I I YII   Lai R W M RWM  

The Journal of hospital infection 20210720


The increasing number of coronavirus disease 2019 (COVID-19) cases in the community has posed a significant epidemic pressure on healthcare settings. When healthcare workers (HCWs) acquire COVID-19, contact tracing and epidemiological investigation might not be adequate for determining the source of transmission. Here, we report a phylogenetic investigation involving two infected HCWs and nine patients to determine whether patient-to-HCW transmission had occurred in a hospital without a previous  ...[more]

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