Repurpose but also (nano)-reformulate! The potential role of nanomedicine in the battle against SARS-CoV2.

ABSTRACT: The coronavirus disease-19 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) has taken the world by surprise. To date, a worldwide approved treatment remains lacking and hence in the context of rapid viral spread and the growing need for rapid action, drug repurposing has emerged as one of the frontline strategies in the battle against SARS-CoV2. Repurposed drugs currently being evaluated against COVID-19 either tackle the replication and spread of SARS-CoV2 or they aim at controlling hyper-inflammation and the rampaged immune response in severe disease. In both cases, the target for such drugs resides in the lungs, at least during the period where treatment could still provide substantial clinical benefit to the patient. Yet, most of these drugs are adm

SUBMITTER: Tammam SN 

PROVIDER: S-EPMC8289726 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature