Rapid antigen detection kit for the diagnosis of SARS-CoV-2 - are we missing asymptomatic patients?

ABSTRACT:

Purpose

To determine the utility, diagnostic accuracy, sensitivity, specificity, and negative predictive value of the laboratory based Covid-19 antigen detection test (Coris Bio- Concept, Gembloux, Belgium) for the diagnosis of SARS-CoV-2 in a tertiary care hospital among symptomatic and asymptomatic patients.

Methods

The nasopharyngeal swab samples were collected from the symptomatic patients and their contacts. The diagnostic accuracy of this antigen kit was determined in comparison to SARS-CoV-2 real-time reverse transcriptase (RT-PCR).

Results

A total of 825 patients fulfilling the inclusion criteria were included in the study; RT-PCR and antigen detection was performed simultaneously for 484 samples to determine the sensitivity and specificity of the test. The ov

SUBMITTER: Kanaujia R 

PROVIDER: S-EPMC8289730 | biostudies-literature | 2021 Oct-Dec

REPOSITORIES: biostudies-literature