Comparative Genomics Reveals Factors Associated with Phenotypic Expression of Wolbachia.

ABSTRACT: Wolbachia is a widespread, vertically transmitted bacterial endosymbiont known for manipulating arthropod reproduction. Its most common form of reproductive manipulation is cytoplasmic incompatibility (CI), observed when a modification in the male sperm leads to embryonic lethality unless a compatible rescue factor is present in the female egg. CI attracts scientific attention due to its implications for host speciation and in the use of Wolbachia for controlling vector-borne diseases. However, our understanding of CI is complicated by the complexity of the phenotype, whose expression depends on both symbiont and host factors. In the present study, we perform a comparative analysis of nine complete Wolbachia genomes with known CI properties in the same genetic host background, Drosophila s

SUBMITTER: Baiao GC 

PROVIDER: S-EPMC8290115 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature