M2aia-Interactive, fast, and memory-efficient analysis of 2D and 3D multi-modal mass spectrometry imaging data.

ABSTRACT:

Background

Mass spectrometry imaging (MSI) is a label-free analysis method for resolving bio-molecules or pharmaceuticals in the spatial domain. It offers unique perspectives for the examination of entire organs or other tissue specimens. Owing to increasing capabilities of modern MSI devices, the use of 3D and multi-modal MSI becomes feasible in routine applications-resulting in hundreds of gigabytes of data. To fully leverage such MSI acquisitions, interactive tools for 3D image reconstruction, visualization, and analysis are required, which preferably should be open-source to allow scientists to develop custom extensions.

Findings

We introduce M2aia (MSI applications for interactive analysis in MITK), a software tool providing interactive and memory-efficient data access

SUBMITTER: Cordes J 

PROVIDER: S-EPMC8290197 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature