Temporal Trends in Neurodevelopmental Outcomes to 2 Years After Extremely Preterm Birth.

ABSTRACT:

Importance

Survival of infants born extremely preterm (EP) (<28 weeks' gestation) has increased since the early 1990s. It is necessary to know whether increased survival is accompanied by increased neurodevelopmental disability.

Objective

To examine changes in major (ie, moderate or severe) neurodevelopmental disability and survival free of major neurodevelopmental disability at 2 years in infants born EP.

Design, setting, and participants

Four prospective longitudinal cohort studies comprising all EP live births at 22 to 27 weeks' gestation from April 1, 2016, to March 31, 2017, and earlier eras (1991-1992, 1997, and 2005), and contemporaneous term-born controls in the state of Victoria, Australia. Among 1208 live births during the periods studied, data were availabl

SUBMITTER: Cheong JLY 

PROVIDER: S-EPMC8290336 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature