Reducing COVID-19 quarantine with SARS-CoV-2 testing: a simulation study.

ABSTRACT:

Objective

To evaluate the effectiveness of SARS-CoV-2 testing on shortening the duration of quarantines for COVID-19 and to identify the most effective choices of testing schedules.

Design

We performed extensive simulations to evaluate the performance of quarantine strategies when one or more SARS-CoV-2 tests were administered during the quarantine. Simulations were based on statistical models for the transmissibility and viral loads of SARS-CoV-2 infections and the sensitivities of available testing methods. Sensitivity analyses were performed to evaluate the impact of perturbations in model assumptions on the outcomes of optimal strategies.

Results

We found that SARS-CoV-2 testing can effectively reduce the length of a quarantine without compromising safety. A singl

SUBMITTER: Peng B 

PROVIDER: S-EPMC8290949 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature