Phase I trial compensation: How much do healthy volunteers actually earn from clinical trial enrollment?

ABSTRACT:

Background/aims

Financial compensation for research participation is a major focus of ethical concern regarding human subject recruitment. Phase I trials are sometimes considered to be a lucrative source of income for healthy volunteers, encouraging some people to become "professional guinea pigs." Yet, little is known about how much these clinical trials actually pay and how much healthy volunteers earn from them.

Methods

As part of a mixed-methods, longitudinal study of healthy volunteers, we required participants to complete clinical trial diaries, or surveys that captured detailed information about screening and enrollment in Phase I trials. Over a 3-year period, participants provided information online or via telephone about each clinical trial for which they screened (

SUBMITTER: Fisher JA 

PROVIDER: S-EPMC8290991 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature