Chances and risks of sodium-glucose cotransporter 2 inhibitors in solid organ transplantation: A review of literatures.

ABSTRACT: Solid organ transplantation offers life-saving treatment for patients with end-organ dysfunction. Patient survival and quality of life have improved over the past few decades as a result of pharmacological development, expansion of the donor pool, technological advances and standardization of practices related to transplantation. Still, transplantation is associated with cardiovascular complications, of which post-transplant diabetes mellitus (PTDM) is one of the most important. PTDM increases mortality, which is best documented in patients who have received kidney and heart transplants. PTDM results from traditional risk factors seen in patients with type 2 diabetes mellitus, but also from specific post-transplant risk factors such as metabolic side effects of immunosuppressive drugs, pos

SUBMITTER: Schwarzenbach M 

PROVIDER: S-EPMC8290999 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature