Ontology highlight
ABSTRACT:
SUBMITTER: Noble C
PROVIDER: S-EPMC8291371 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Noble Christopher C Carlson Kent K Neumann Erica E Lewis Bradley B Dragomir-Daescu Dan D Lerman Amir A Erdemir Ahmet A Young Melissa M
Medicine in novel technology and devices 20200824
Peripheral artery disease (PAD) results from the buildup of atherosclerotic plaque in the arterial wall, can progress to severe ischemia and lead to tissue necrosis and limb amputation. We evaluated a means of assessing PAD mechanics <i>ex vivo</i> using ten human peripheral arteries with PAD. Pressure-inflation testing was performed at six physiological pressure intervals ranging from 10-200 mmHg. These vessels were imaged with IVUS-VH to determine plaque composition and change in vessel struct ...[more]