Durable superamphiphobic silica aerogel surfaces for the culture of 3D cellular spheroids.

ABSTRACT: The 3D multicellular spheroids with intact cell-cell junctions have major roles in biological research by virtue of their unique advantage of mimicking the cellular physiological environments. In this work, a durable superamphiphobic silica aerogel surface (SSAS) has been fabricated for the upward culture of 3D multicellular spheroids. Poly(3,4-ethylenedioxythiophene) (PEDOT) was first electrodeposited on a conductive steel mesh as a first template for porous silica coating. Soot particles were then applied as a second template to construct a cauliflower-like silica aerogel nanostructure. After fluorination, a hierarchical structure with re-entrant curvature was finally fabricated as a durable superamphiphobic surface. This superamphiphobic surface also presented excellent antifouling towa

SUBMITTER: Xu L 

PROVIDER: S-EPMC8291414 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature