The association of severe anemia, red blood cell transfusion and necrotizing enterocolitis in neonates.

ABSTRACT:

Background

The relationship between severe anemia, red blood cell transfusion and Neonatal necrotizing enterocolitis (NEC) remains controversial. The purpose of this study was to determine the association of severe anemia and RBC transfusion with NEC in neonates.

Methods

The clinical characteristics of NEC were observed in 467 infants with different birth weights from January 2012 to July 2020. A 1:1 ratio case-control study was performed in very low birth weight (VLBW) infants. Severe anemia, RBC transfusion, and confounding factors, including maternal and perinatal complications, feeding, and antibiotics administration were collected in both groups. Univariate and multivariate analyses were used to investigate effects on the risk of NEC.

Results

The day of NEC onset

SUBMITTER: Song J 

PROVIDER: S-EPMC8291682 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature