Organophosphate pesticides and progression of chronic kidney disease among children: A prospective cohort study.

ABSTRACT:

Background

Growing evidence suggests that exposure to environmental chemicals, such as pesticides, impacts renal function and chronic kidney disease (CKD). However, it is not clear if pesticides may affect CKD progression and no studies exist in children.

Objectives

The objective of this study was to examine associations between serially measured urinary OP pesticide metabolites and clinical and laboratory measures of kidney function over time among children with CKD.

Methods

This study used data on 618 participants enrolled in the CKD in Children study (CKiD), a cohort study of pediatric CKD patients from the US and Canada. Children were followed over an average of 3.0 years (standard deviation (SD) = 1.6) between 2005 and 2015. In serially collected urine samples ov

SUBMITTER: Jacobson MH 

PROVIDER: S-EPMC8292180 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature