The associations of phthalate biomarkers during pregnancy with later glycemia and lipid profiles.

ABSTRACT:

Background

Pregnancy induces numerous cardiovascular and metabolic changes. Alterations in these sensitive processes may precipitate long-term post-delivery health consequences. Studies have reported associations between phthalates and metabolic complications of pregnancy, but no study has investigated metabolic outcomes beyond pregnancy.

Objectives

To examine associations of exposure to phthalates during pregnancy with post-delivery metabolic health.

Design

We quantified 15 urinary phthalate biomarker concentrations during the second and third trimesters among 618 pregnant women from Mexico City. Maternal metabolic health biomarkers included fasting blood measures of glycemia [glucose, insulin, Homeostatic Model Assessment of Insulin Resistance [HOMA-IR], % hemoglobi

SUBMITTER: Wu H 

PROVIDER: S-EPMC8292182 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature