The effect of prenatal temperature and PM_2.5 exposure on birthweight: Weekly windows of exposure throughout the pregnancy.

ABSTRACT:

Background

Birthweight is a strong predictor of normal growth, healthy development, and survival. Several studies have found associations between temperature, fine particulate matter (PM_2.5), and birth weight. However, the relevant timing of exposures varies between studies and is yet unclear. Therefore, we assessed the difference in term birthweight (TBW) associated with weekly exposure to temperature and PM_2.5 throughout 37 weeks of gestation.

Methods

We included all singleton live term births in Massachusetts, U.S between 2004 and 2015 (n = 712,438). Weekly PM_2.5 and temperature predictions were estimated on a 1 km grid from satellite-based models. We utilized a distributed lag nonlinear model (DLNM) to estimate the difference in TBW assoc

SUBMITTER: Yitshak-Sade M 

PROVIDER: S-EPMC8292186 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature