Effectiveness and Harms of High-Flow Nasal Oxygen for Acute Respiratory Failure: An Evidence Report for a Clinical Guideline From the American College of Physicians.

ABSTRACT:

Background

Use of high-flow nasal oxygen (HFNO) for treatment of adults with acute respiratory failure (ARF) has increased.

Purpose

To assess HFNO versus noninvasive ventilation (NIV) or conventional oxygen therapy (COT) for ARF in hospitalized adults.

Data sources

English-language searches of MEDLINE, Embase, CINAHL, and Cochrane Library from January 2000 to July 2020; systematic review reference lists.

Study selection

29 randomized controlled trials evaluated HFNO versus NIV (k = 11) or COT (k = 21).

Data extraction

Data extraction by a single investigator was verified by a second, 2 investigators assessed risk of bias, and evidence certainty was determined by consensus.

Data synthesis

Results are reported separately for HFNO versu

SUBMITTER: Baldomero AK 

PROVIDER: S-EPMC8292205 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature