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Three diketomorpholines from a Penicillium sp. (strain G1071).

ABSTRACT: Three previously undescribed diketomorpholine natural products, along with the known phenalenones, herqueinone and norherqueinone, were isolated from the mycoparasitic fungal strain G1071, which was identified as a Penicillium sp. in the section Sclerotiora. The structures were established by analyzing NMR data and mass spectrometry fragmentation patterns. The absolute configurations of deacetyl-javanicunine A, javanicunine C, and javanicunine D, were assigned by examining ECD spectra and Marfey's analysis. The structural diversity generated by this fungal strain was interesting, as only a few diketomorpholines (~17) have been reported from nature.

SUBMITTER: Al Subeh ZY

PROVIDER: S-EPMC8292221 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature

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Three diketomorpholines from a Penicillium sp. (strain G1071).

Al Subeh Zeinab Y ZY Raja Huzefa A HA Burdette Joanna E JE Falkinham Joseph O JO Hemby Scott E SE Oberlies Nicholas H NH

Phytochemistry 20210620

Three previously undescribed diketomorpholine natural products, along with the known phenalenones, herqueinone and norherqueinone, were isolated from the mycoparasitic fungal strain G1071, which was identified as a Penicillium sp. in the section Sclerotiora. The structures were established by analyzing NMR data and mass spectrometry fragmentation patterns. The absolute configurations of deacetyl-javanicunine A, javanicunine C, and javanicunine D, were assigned by examining ECD spectra and Marfey ...[more]

PMID: 34157637

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