Post-keratoplasty Infectious Keratitis: Epidemiology, Risk Factors, Management, and Outcomes.

ABSTRACT: Post-keratoplasty infectious keratitis (PKIK) represents a unique clinical entity that often poses significant diagnostic and therapeutic challenges. It carries a high risk of serious complications such as graft rejection and failure, and less commonly endophthalmitis. Topical corticosteroids are often required to reduce the risk of graft rejection but their use in PKIK may act as a double-edged sword, particularly in fungal infection. The increased uptake in lamellar keratoplasty in the recent years has also led to complications such as graft-host interface infectious keratitis (IIK), which is particularly difficult to manage. The reported incidence of PKIK differs considerably across different countries, with a higher incidence observed in developing countries (9.2-11.9%) than developed

SUBMITTER: Song A 

PROVIDER: S-EPMC8292647 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature