Single isocenter SRS using CAVMAT offers improved robustness to commissioning and treatment delivery uncertainty compared to VMAT.

ABSTRACT:

Purpose

In this study, we evaluate and compare single isocenter multiple target VMAT (SIMT) and Conformal Arc Informed VMAT (CAVMAT) radiosurgery's sensitivity to uncertainties in dosimetric leaf gap (DLG) and treatment delivery. CAVMAT is a novel planning technique that uses multiple target conformal arcs as the starting point for limited inverse VMAT optimization.

Methods

All VMAT and CAVMAT plans were recalculated with DLG values of 0.4, 0.8, and 1.2 mm. DLG effect on V_6Gy [cc], V_12Gy [cc], and V_16Gy [cc], and target dose was evaluated. Plans were delivered to a Delta⁴ (ScandiDos, Madison, WI) phantom and gamma analysis performed with varying criteria. Log file analysis was performed to evaluate MLC positional error. Sixteen tar

SUBMITTER: Cullom ET 

PROVIDER: S-EPMC8292691 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature