Role of opiorphin genes in prostate cancer growth and progression.
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ABSTRACT:
SUBMITTER: Mukherjee A
PROVIDER: S-EPMC8293029 | biostudies-literature | 2021 Jun
REPOSITORIES: biostudies-literature
Publications
Role of opiorphin genes in prostate cancer growth and progression.
Mukherjee Amarnath A Park Augene A Wang Li L Davies Kelvin P KP
Future oncology (London, England) 20210217 17
<b>Background:</b> We describe the first studies investigating a role for opiorphin genes (<i>PROL1</i>, <i>SMR3A</i> and <i>SMR3B</i>) in prostate cancer (PrCa). <b>Materials & methods:</b> Databases and PrCa tissue arrays were screened for opiorphin expression. Xenografted tumor growth of human PrCa cells overexpressing <i>PROL1</i> was compared with controls in nude mice. Modulated gene expression by overexpression of <i>PROL1</i> was determined by RNA sequencing. <b>Results:</b> PrCa is asso ...[more]
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