Ontology highlight
ABSTRACT:
SUBMITTER: Sharaf K
PROVIDER: S-EPMC8293237 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Sharaf Kariem K Lechner Axel A Haider Stefan P SP Wiebringhaus Robert R Walz Christoph C Kranz Gisela G Canis Martin M Haubner Frank F Gires Olivier O Baumeister Philipp P
Current oncology (Toronto, Ont.) 20210719 4
Cancer stem cells (CSCs) are accountable for the progress of head and neck squamous cell carcinoma (HNSCC). This exploratory study evaluated the expression of molecular CSC markers in different tissues of HNSCC patients. Tissue specimens of primary tumor, lymph node metastases and macroscopically healthy mucosa of 12 consecutive HNSCC patients, that were treated with surgery and adjuvant radio(chemo)therapy upon indication, were collected. Samples were assessed for the expression of p16 as a sur ...[more]