The Behavioral and Psychological Symptoms of Dementia in Down Syndrome Scale (BPSD-DS II): Optimization and Further Validation.

ABSTRACT:

Background

People with Down syndrome (DS) are at high risk to develop Alzheimer's disease dementia (AD). Behavioral and psychological symptoms of dementia (BPSD) are common and may also serve as early signals for dementia. However, comprehensive evaluation scales for BPSD, adapted to DS, are lacking. Therefore, we previously developed the BPSD-DS scale to identify behavioral changes between the last six months and pre-existing life-long characteristic behavior.

Objective

To optimize and further study the scale (discriminative ability and reliability) in a large representative DS study population.

Methods

Optimization was based on item irrelevance and clinical experiences obtained in the initial study. Using the shortened and refined BPSD-DS II, informant interviews we

SUBMITTER: Dekker AD 

PROVIDER: S-EPMC8293661 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature