IHP-PING-generating integrated human protein-protein interaction networks on-the-fly.

ABSTRACT: Advances in high-throughput sequencing technologies have resulted in an exponential growth of publicly accessible biological datasets. In the 'big data' driven 'post-genomic' context, much work is being done to explore human protein-protein interactions (PPIs) for a systems level based analysis to uncover useful signals and gain more insights to advance current knowledge and answer specific biological and health questions. These PPIs are experimentally or computationally predicted, stored in different online databases and some of PPI resources are updated regularly. As with many biological datasets, such regular updates continuously render older PPI datasets potentially outdated. Moreover, while many of these interactions are shared between these online resources, each resource includes it

SUBMITTER: Mazandu GK 

PROVIDER: S-EPMC8293832 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature