Vasoactive pharmacologic therapy in cardiogenic shock: a critical review.

ABSTRACT:

Background

Cardiogenic shock (CS) is an acute complex condition leading to morbidity and mortality. Vasoactive medications, such as vasopressors and inotropes are considered the cornerstone of pharmacological treatment of CS to improve end-organ perfusion by increasing cardiac output (CO) and blood pressure (BP), thus preventing multiorgan failure.

Objective

A critical review was conducted to analyze the currently available randomized studies of vasoactive agents in CS to determine the indications of each agent and to critically appraise the methodological quality of the studies.

Methods

PubMed database search was conducted to identify randomized controlled trials (RCTs) on vasoactive therapy in CS. After study selection, the internal validity of the selected studies

SUBMITTER: Kaddoura R 

PROVIDER: S-EPMC8293961 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature