Hemodynamic conditions that favor bleb formation in cerebral aneurysms.

ABSTRACT:

Background

Although it is generally believed that blebs represent weaker spots in the walls of intracranial aneurysms (IAs), it is largely unknown which aneurysm characteristics favor their development.

Objective

To investigate possible associations between aneurysm hemodynamic and geometric characteristics and the development of blebs in intracranial aneurysms.

Methods

A total of 270 IAs in 199 patients selected for surgical clipping were studied. Blebs were visually identified and interactively marked on patient-specific vascular models constructed from presurgical images. Blebs were then deleted from the vascular reconstruction to approximate the aneurysm before bleb formation. Computational fluid dynamics studies were performed in these models and in cases without

SUBMITTER: Salimi Ashkezari SF 

PROVIDER: S-EPMC8294198 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature