The status of causality in biological databases: data resources and data retrieval possibilities to support logical modeling.

ABSTRACT: Causal molecular interactions represent key building blocks used in computational modeling, where they facilitate the assembly of regulatory networks. Logical regulatory networks can be used to predict biological and cellular behaviors by system perturbations and in silico simulations. Today, broad sets of causal interactions are available in a variety of biological knowledge resources. However, different visions, based on distinct biological interests, have led to the development of multiple ways to describe and annotate causal molecular interactions. It can therefore be challenging to efficiently explore various resources of causal interaction and maintain an overview of recorded contextual information that ensures valid use of the data. This review lists the different types of public re

SUBMITTER: Toure V 

PROVIDER: S-EPMC8294520 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature