Effects of depth of neuromuscular blockade on the BIS-guided propofol requirement: A randomized controlled trial.

ABSTRACT:

Background

Deep neuromuscular blockade is considered beneficial for improving the surgical space condition during laparoscopic surgery. Adequacy of the surgical space condition may affect the anesthetists' decision regarding titration of depth of anesthesia. We investigated whether deep neuromuscular blockade reduces the propofol requirement under bispectral index monitoring compared to moderate neuromuscular blockade.

Methods

Adult patients undergoing elective laparoscopic colorectal surgery were randomly allocated to a moderate or deep group. A train-of-four count of 1-2 in the moderate group, and a post-tetanic count of 1-2 in the deep group, were maintained by continuous infusion of rocuronium. The induction and maintenance of anesthesia were achieved by target-controlle

SUBMITTER: Nam SW 

PROVIDER: S-EPMC8294904 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature