Exercising under particulate matter exposure: Providing theoretical support for lung deposition and its relationship with COVID-19.

ABSTRACT: The aim of the present study was to investigate lung particulate matter (PM) deposition during endurance exercise and provide a new insight concerning how SARS-CoV-2 could be carried into the respiratory tract. The anatomical and physiological characteristics of the Human Respiratory Tract model were considered for modeling the lung PM deposition during exercise. The Monte Carlo method was performed to randomly generate different values of PM concentrations (1.0, 2.5, and 10.0 μm), minute ventilation, and duration of exercise at moderate, heavy, and severe exercise intensity domains. Compared to moderate and severe intensities, during heavy exercise (75-115 L‧min-1, duration of 10.0-60.0 min) there is greater lung deposition in the bronchiolar region (p < 0.01). In turn, there is greater d

SUBMITTER: Cruz R 

PROVIDER: S-EPMC8295105 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature