Characterization and correction of cardiovascular motion artifacts in diffusion-weighted imaging of the pancreas.

ABSTRACT:

Purpose

To assess the effects of cardiovascular-induced motion on conventional DWI of the pancreas and to evaluate motion-robust DWI methods in a motion phantom and healthy volunteers.

Methods

3T DWI was acquired using standard monopolar and motion-compensated gradient waveforms, including in an anatomically accurate pancreas phantom with controllable compressive motion and healthy volunteers (n = 8, 10). In volunteers, highly controlled single-slice DWI using breath-holding and cardiac gating and whole-pancreas respiratory-triggered DWI were acquired. For each acquisition, the ADC variability across volunteers, as well as ADC differences across parts of the pancreas were evaluated.

Results

In motion phantom scans, conventional DWI led to biased ADC, whereas motion-co

SUBMITTER: Geng R 

PROVIDER: S-EPMC8295219 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature