Noninvasive ventilation vs. high-flow nasal cannula oxygen for preoxygenation before intubation in patients with obesity: a post hoc analysis of a randomized controlled trial.

ABSTRACT:

Background

Critically ill patients with obesity may have an increased risk of difficult intubation and subsequent severe hypoxemia. We hypothesized that pre-oxygenation with noninvasive ventilation before intubation as compared with high-flow nasal cannula oxygen may decrease the risk of severe hypoxemia in patients with obesity.

Methods

Post hoc subgroup analysis of critically ill patients with obesity (body mass index ≥ 30 kg·m^-2) from a multicenter randomized controlled trial comparing preoxygenation with noninvasive ventilation and high-flow nasal oxygen before intubation of patients with acute hypoxemic respiratory failure (PaO₂/FiO₂ < 300 mm Hg). The primary outcome was the occurrence of severe hypoxemia (pulse oximetry < 80%) during th

SUBMITTER: Rodriguez M 

PROVIDER: S-EPMC8295638 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature