Evaluation of compounded trilostane packets for dogs with naturally occurring hyperadrenocorticism.

ABSTRACT:

Background

Dogs treated for naturally occurring hyperadrenocorticism (NOH) in Korea often appear to require higher doses of trilostane than recommended by authors in the United States, Europe, or the United Kingdom. This phenomenon may be related to compounding trilostane into packets, which is a common practice among veterinary clinics in Korea.

Objective

Analyze packets filled by hand and others filled using a semi-automatic packing device for accuracy of trilostane strength.

Animals

Medication packets prepared for 3 dogs with preexisting prescriptions for NOH were analyzed.

Method

A trilostane assay was developed for analysis. Trilostane (Vetoryl) capsules were used as clinical controls. Forty-four medication packets containing trilostane (Vetoryl), prepared

SUBMITTER: Nam S 

PROVIDER: S-EPMC8295693 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature