Development Over Time of the Population-Attributable Risk Fraction for Cannabis Use Disorder in Schizophrenia in Denmark.

ABSTRACT:

Importance

Cannabis use and potency of cannabis have increased during the past 2 decades. If the association between cannabis use and schizophrenia is causal, this should be reflected in an increase in the proportion of cases of schizophrenia being attributable to cannabis, the population-attributable risk fraction (PARF).

Objective

To determine whether the PARF for cannabis use disorder in schizophrenia has increased over time.

Design, setting, and participants

This nationwide, register-based historical prospective cohort study included all people in Denmark born before December 31, 2000, who were alive and 16 years or older at some point from January 1, 1972, to December 31, 2016. Data analysis was performed from August 2020 to April 2021.

Exposure

Diagnosis

SUBMITTER: Hjorthoj C 

PROVIDER: S-EPMC8295899 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature