Ontology highlight
ABSTRACT:
SUBMITTER: Zhang QY
PROVIDER: S-EPMC8295919 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Zhang Qiu-Yan QY Deng Cheng-Lin CL Liu Jing J Li Jia-Qi JQ Zhang Hong-Qing HQ Li Na N Zhang Ya-Nan YN Li Xiao-Dan XD Zhang Bo B Xu Yi Y Ye Han-Qing HQ
The Journal of general virology 20210501 5
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus, which is highly pathogenic and classified as a biosafety level 3 (BSL-3) agent, has greatly threatened global health and efficacious antivirals are urgently needed. The high requirement of facilities to manipulate the live virus has limited the development of antiviral study. Here, we constructed a reporter replicon of SARS-CoV-2, which can be handled in a BSL-2 laboratory. The Renilla luciferase activity effectively reflect ...[more]