Conservative oxygen therapy for critically ill patients: a meta-analysis of randomized controlled trials.

ABSTRACT:

Objective

Conservative oxygen strategy is recommended in acute illness while its benefit in ICU patients remains controversial. Therefore, we sought to conduct a systematic review and meta-analysis to examine such oxygen strategies' effect and safety in ICU patients.

Methods

We searched PubMed, Embase, and the Cochrane database from inception to Feb 15, 2021. Randomized controlled trials (RCTs) that compared a conservative oxygen strategy to a conventional strategy in critically ill patients were included. Results were expressed as mean difference (MD) and risk ratio (RR) with a 95% confidence interval (CI). The primary outcome was the longest follow-up mortality. Heterogeneity, sensitivity analysis, and publication bias were also investigated to test the robustness of the p

SUBMITTER: Chen XL 

PROVIDER: S-EPMC8295978 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature