The prognostic significance of large vessel occlusion in stroke patients treated by intravenous thrombolysis.

ABSTRACT:

Purpose

According to guidelines, to shorten the treatment window, acute ischaemic stroke (AIS) treatment by intravenous thrombolysis (IVT) can be done based on the results of head computed tomography (CT) without contrast. The impact of large vessel occlusion (LVO) on computed tomography angiography (CTA) in stroke prognosis in patients treated IVT or IVT and mechanical thrombectomy (MT), where indicated, has not yet been studied systematically. We investigated the influence of LVO in consecutive AIS patients on haemorrhagic transformation (HT) on CT 24 h after treatment, mRS < 2 on discharge (unfavourable outcome), and in-hospital mortality.

Material and methods

We analysed several parameters within 24 h after AIS: demographics, risk factors, mRS score pre-stroke, NIHSS upo

SUBMITTER: Derbisz JM 

PROVIDER: S-EPMC8297478 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature