The Experience of OFF Periods in Parkinson's Disease: Descriptions, Triggers, and Alleviating Factors.

ABSTRACT:

Purpose

Wearing off of Parkinson's disease medication is common, but triggers and coping strategies for this transient phenomenon are poorly understood. We aimed to assess the lived experience of OFF periods for people with Parkinson's disease.

Methods

Participants in the longitudinal Fox Insight study who endorsed OFF periods were invited to complete a survey consisting of both multiple-choice and free-text responses. Descriptive statistics were used to summarize multiple-choice responses, and free-text responses were classified into themes through iterative discussion by 3 movement disorders specialists.

Results

A total of 2110 participants (52.4% male) completed the survey. Tremor was the most common description of OFF periods (n=1038, 49.2%), followed by gait chan

SUBMITTER: Mantri S 

PROVIDER: S-EPMC8297496 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature