Recurrent Tuberculosis Disease in Singapore.

ABSTRACT:

Background

Previously treated (ie, recurrent) tuberculosis (TB) cases account for approximately 7%-8% of incident TB globally and in Singapore. Molecular fingerprinting has enabled the differentiation of these patients into relapsed or reinfection cases.

Methods

Patient demographics, disease characteristics, and treatment information were obtained from the national TB notification registry and TB Control Unit. We performed a retrospective, case-control study to evaluate factors associated with recurrent TB disease in Singapore citizens and permanent residents with culture-positive TB from 2006 to 2013 and who developed a second episode of culture-positive TB up to 2016 using multivariable logistic regression analyses.

Results

Ninety-one cases with culture-positive fir

SUBMITTER: Gan SH 

PROVIDER: S-EPMC8297698 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature