Powerful detection of polygenic selection and evidence of environmental adaptation in US beef cattle.

ABSTRACT: Selection on complex traits can rapidly drive evolution, especially in stressful environments. This polygenic selection does not leave intense sweep signatures on the genome, rather many loci experience small allele frequency shifts, resulting in large cumulative phenotypic changes. Directional selection and local adaptation are changing populations; but, identifying loci underlying polygenic or environmental selection has been difficult. We use genomic data on tens of thousands of cattle from three populations, distributed over time and landscapes, in linear mixed models with novel dependent variables to map signatures of selection on complex traits and local adaptation. We identify 207 genomic loci associated with an animal's birth date, representing ongoing selection for monogenic and p

SUBMITTER: Rowan TN 

PROVIDER: S-EPMC8297814 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature