Information flow, cell types and stereotypy in a full olfactory connectome.

ABSTRACT: The hemibrain connectome provides large-scale connectivity and morphology information for the majority of the central brain of Drosophila melanogaster. Using this data set, we provide a complete description of the Drosophila olfactory system, covering all first, second and lateral horn-associated third-order neurons. We develop a generally applicable strategy to extract information flow and layered organisation from connectome graphs, mapping olfactory input to descending interneurons. This identifies a range of motifs including highly lateralised circuits in the antennal lobe and patterns of convergence downstream of the mushroom body and lateral horn. Leveraging a second data set we provide a first quantitative assessment of inter- versus intra-individual stereotypy.

SUBMITTER: Schlegel P 

PROVIDER: S-EPMC8298098 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature