Six-month effects of modified Atkins diet implementation on indices of cardiovascular disease risk in adults with epilepsy.

ABSTRACT:

Background/aims

Ketogenic diet therapies (KDTs) offer a needed therapeutic option for patients with drug-resistant epilepsy. The current study investigated biochemical and anthropometric indices of cardiovascular disease (CVD) risk in adults with epilepsy treated with KDT over 6 months.

Method

65 adults with epilepsy naïve to diet therapy were enrolled in a prospective longitudinal study and instructed on modified Atkins diet (MAD) use. Seizure frequency, anthropometric measures, blood levels of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoproteins A1 and B, and lipoprotein sub-fractions were assessed at baseline, 3 months, and 6 months.

Results

Subsequent to study enrollment, 34 participants were

SUBMITTER: McDonald TJW 

PROVIDER: S-EPMC8298606 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature