Approaches for Health Effect Characterization in Risk-Benefit Assessment of Foods: A Comparative Case Study.

ABSTRACT: One of the challenges in quantitative risk-benefit assessment (RBA) of foods is the choice of approach for health effect characterization to estimate the health impact of dietary changes. The purpose of health effect characterization is to describe an association between intake of a food or food component and a health effect in terms of a dose-response relationship. We assessed the impact of the choice of approach for health effect characterization in RBA in two case studies based on substitution of (i) white rice by brown rice and (ii) unprocessed red meat by vegetables. We explored this by comparing the dose-response relations linking a health effect with (i) a food component present in the food, (ii) a food based on non-specified substitution analyses, and (iii) a food based on specifie

SUBMITTER: Thomsen ST 

PROVIDER: S-EPMC8298756 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature