Tremor analysis with wearable sensors correlates with outcome after thalamic deep brain stimulation.

ABSTRACT:

Introduction

Thalamic deep brain stimulation (DBS) provides excellent tremor control in most patients with essential tremor (ET). However, not all tremor patients show clinically significant improvement after DBS surgery. Currently, there is no reliable clinical or instrument-based measure to predict how patients respond to DBS. Therefore, we set out to provide a method for tremor outcome prediction prior to surgery.

Methods

We retrospectively analysed quantitative tremor data collected with inertial measurement units (IMU) in 13 patients who underwent DBS surgery in the ventral intermediate nucleus of the thalamus (VIM). All patients were diagnosed with either ET or ET-plus according to current diagnostic criteria of the movement disorder society. We used linear and logisti

SUBMITTER: Ruegge D 

PROVIDER: S-EPMC8298798 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature