Impact of abobotulinumtoxinA on the clinical features of cervical dystonia in routine practice.

ABSTRACT:

Introduction

The efficacy and safety of abobotulinumtoxinA in the management of cervical dystonia has been established in randomized, controlled trials that use a selected trial population. In this meta-analysis of observational data, we evaluated the real-life effectiveness of abobotulinumtoxinA as delivered in routine clinical practice.

Methods

Meta-analysis of patient-level data for adult patients with cervical dystonia treated with abobotulinumtoxinA from three prospective, multicenter, observational studies (NCT01314365, NCT00833196 and NCT01753349).

Results

We report data for patients treated with abobotulinumtoxinA over one injection cycle at 181 neurology centers in 35 countries. CD clinical features as assessed by Toronto Western Spasmodic Torticollis Rating

SUBMITTER: Trosch RM 

PROVIDER: S-EPMC8298811 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature