Associations between oxygen delivery and cardiac index with hyperlactatemia during cardiopulmonary bypass.

ABSTRACT:

Objective

Metabolism management plays an essential role during cardiopulmonary bypass (CPB). There are different metabolic management devices integrated to heart-lung machines; the most commonly used and accepted metabolic target is indexed oxygen delivery (DO_2i) (280 mL/min/m²) and cardiac index (CI) (2.4 L/min/m²), which can be managed independently or according to other metabolic parameters. Our objective was to compare lactate production during CPB procedures using different metabolic management: DO_2i in relation to indexed oxygen extraction ratio (O₂ER_i) and CI in relation to mixed venous oxygen saturation (SvO₂).

Methods

Data on 500 CPB procedures were retrospectively collected in a specialize

SUBMITTER: Condello I 

PROVIDER: S-EPMC8299069 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature